Benzene, 1-fluoro-2-isocyanato-4-methyl- (9CI)

Benzene, 1-fluoro-2-isocyanato-4-methyl- (9CI) - Names and Identifiers

Name	2-Fluoro-5-Methylphenyl Isocyanate
Synonyms	2-Fluoro-5-Methylphenyl Isocyanate 2-FLUORO-5-METHYLPHENYL ISOCYANATE 1-fluoro-2-isocyanato-4-methylbenzene 1-fluoro-2-isocyanato-4-Methylbenzene Benzene, 1-fluoro-2-isocyanato-4-methyl- Benzene, 1-fluoro-2-isocyanato-4-methyl- (9CI) 4-Fluoro-3-isocyanatotoluene, 1-Fluoro-2-isocyanato-4-methylbenzene
CAS	190774-50-6
InChI	InChI=1/C8H6FNO/c1-6-2-3-7(9)8(4-6)10-5-11/h2-4H,1H3

Benzene, 1-fluoro-2-isocyanato-4-methyl- (9CI) - Physico-chemical Properties

Molecular Formula	C8H6FNO
Molar Mass	151.14
Density	1.159g/mLat 25°C(lit.)
Boling Point	192°C(lit.)
Flash Point	185°F
Vapor Presure	0.229mmHg at 25°C
Storage Condition	-20°C
Sensitive	Moisture Sensitive/Lachrymatory
Refractive Index	n20/D 1.511(lit.)
Physical and Chemical Properties	Sensitivity: moiure Sensitive/Lachrymatory WGK Germany:3

Benzene, 1-fluoro-2-isocyanato-4-methyl- (9CI) - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
UN IDs	2206
WGK Germany	3
Hazard Note	Toxic/Corrosive/Lachrymatory/Moisture Sensitive

Benzene, 1-fluoro-2-isocyanato-4-methyl- (9CI) - Introduction

2-Fluoro-5-Methylphenyl isocyyanate, the chemical formula is C8H6FNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: 2-Fluoro-5-Methylphenyl Isocyanate is a colorless liquid.
2. Density: about 1.26 g/cm.
3. Melting Point: About -36 ℃.
4. Boiling point: About 156-157 ℃.
5. Solubility: Soluble in organic solvents such as ether and dichloromethane.

Use:
2-Fluoro-5-Methylphenyl Isocyanate is mainly used in organic synthesis in the field of chemistry. It can be used as a synthetic intermediate for the preparation of organic compounds such as pharmaceuticals, dyes, polymers and coatings.

Method:
Under normal circumstances, 2-Fluoro-5-Methylphenyl Isocyanate can be prepared by fluorination-with cyanide-with methylene-benzylamine.

Safety Information:
When using 2-Fluoro-5-Methylphenyl Isocyanate, you need to pay attention to the following safety precautions:
1. 2-Fluoro-5-Methylphenyl Isocyanate may cause irritation to the skin, eyes and respiratory tract, so contact should be avoided. Personal protective equipment such as gloves, masks and goggles should be worn during operation.
2. In the process of operation to prevent the inhalation of 2-Fluoro-5-Methylphenyl Isocyanate steam, to ensure that the operating place is well ventilated.
3. During storage and transportation, avoid contact of 2-Fluoro-5-Methylphenyl Isocyanate with combustible substances, oxidants and strong bases.
4. In case of fire, dry powder extinguishing agent or carbon dioxide fire extinguisher should be used to extinguish the fire.

Before using 2-Fluoro-5-Methylphenyl Isocyanate, be sure to read and follow the relevant chemical safety procedures. If poisoning or discomfort occurs, seek medical attention.

Last Update：2024-04-09 20:49:11